The hosts completely dominated the first half, as North Macedonia hardly had any shots on their goal. Stole Dimitrievski was certainly the busier of the two goalkeepers, with Mads Hermansen standing in for the injured Kasper Schmeichel for the Danes.
Nonetheless, it was Joakim Mæhle who had the game’s first meaningful chance, but after finding his way into the penalty box, Dimitrievski pulled off a decent stop.
However, Hermansen had to make an even better save to keep out Darko Churlinov’s dangerous free-kick, which acted as a small warning sign.
Alexander Bah struck just wide before Pierre-Emile Hojbjerg tested Dimitrievski again, but Denmark could not find the breakthrough before the break.
However, the Danes did not have to wait long into the second half to finally take the lead for the fifth time in seven home matches, and it was Mikkel Damsgaard who got the ball rolling by firing a rebound into the corner.
The Brentford man then turned provider for Gustav Isaksen, who controlled his cross before striking in off the post to send his team on their way.
A quickfire double from the winger then made sure of victory before the hour mark, as he too capitalised on a rebound inside the box.
Rasmus Højlund wanted to get in on the act as Denmark’s top scorer in qualifying, but he lashed an effort wide as the match approached its latter stages.
The Danes did add a fourth, though, as two veterans and former Brentford teammates combined, with Christian Eriksen finding Christian Nørgaard from a corner, and the now Arsenal midfielder producing a bullet header into the net.
As a result, North Macedonia’s dream of reaching a first-ever World Cup finals comes to an end, with the Lions well and truly tamed here.